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Peer-reviewed study

Omega-3 works as an add-on, not an exercise replacement

The combined effects of omega-3 polyunsaturated fatty acid supplementation and exercise training on body composition and cardiometabolic health in adults: A systematic review and meta-analysis

SupplementsSystematic review and meta-analysis2025

Last updated 2026-07-21

Source details

PubMed-linked study details.

Authors
Khalafi et al.
Journal
Clinical Nutrition ESPEN. 2025.
Identifiers
PMID 39848543 · DOI 10.1016/j.clnesp.2025.01.022

Honest limits

What this study does not prove.

The trials differed in age, exercise, supplement use, and outcomes, and some health markers were mixed, so fish oil cannot guarantee extra fat loss or better heart health.

Kris's practical takeaway

Here's what to do with it.

Omega-3 belongs alongside a real exercise plan, with progress judged across strength, body composition, and health markers instead of one scale number.

Ways to use it

Safe ways to apply it.

Supplements belong on top of exercise, not instead of it

One scale number cannot summarize the whole result

Mixed findings are still useful findings

Related questions

Questions this research helps answer.

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FAQ

Quick questions

What is the practical takeaway from this study?

Omega-3 belongs alongside a real exercise plan, with progress judged across strength, body composition, and health markers instead of one scale number.

What does this study not prove?

The trials differed in age, exercise, supplement use, and outcomes, and some health markers were mixed, so fish oil cannot guarantee extra fat loss or better heart health.

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