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Peer-reviewed study

Lifting protects muscle during fat loss

Effect of resistance exercise on body composition, muscle strength and cardiometabolic health during dietary weight loss in people living with overweight or obesity: a systematic review and meta-analysis

FitnessSystematic review and meta-analysis2025

Last updated 2026-09-14

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Kris Oddo, NASM-certified personal trainer, is the founder and head coach of Gains From Geebs (Geebs Coaching), a 1:1 online fitness coaching practice.

Quick answer

What this study found

Binmahfoz et al. (2025, BMJ Open Sport & Exercise Medicine, PMID 40909191, DOI 10.1136/bmjsem-2024-002363) reviewed 25 randomized trials in people living with overweight or obesity. Adding resistance exercise to dietary weight loss did not meaningfully increase total bodyweight loss, but it protected fat-free mass (SMD 0.40), increased fat-mass loss (SMD -0.36), and improved muscle strength (SMD 2.36) compared with diet alone. Cardiometabolic changes were less consistent, so the most defensible answer is this: lift while dieting to make more of the weight loss come from fat and less from muscle, not because lifting magically makes the scale fall faster.

How strong is this kind of study?

  1. Reviews of many studiesThis study
  2. Controlled trials
  3. Observational
  4. Narrative reviews

Systematic review and meta-analysis. Heavier plates are built from more studies, so they move less when the next one lands.

At a glance

What kind of study this is

Strongest evidence

This pools results from many separate studies, so it carries more weight than any single trial on its own.

Design
Systematic review and meta-analysis
Published
2025
Journal
BMJ Open Sport & Exercise Medicine
Reference
PMID 40909191

Source details

Who ran it, and where to read it.

Authors
Binmahfoz et al.

Honest limits

What this study does not prove.

The strongest findings were body composition and strength outcomes. The review did not show that resistance exercise makes the scale drop faster, fixes every cardiometabolic marker, or guarantees the same response for every person living with overweight or obesity.

Kris Oddo, NASM-CPT, in the gym
Kris Oddo, NASM-CPT. The study is the evidence; the paragraph below is what he actually does with it.

Kris's practical takeaway

Here's what to do with it.

During a diet phase, lifting may not make the scale drop faster, but it can improve fat-mass loss, protect fat-free mass, and preserve strength. Keep the plan simple: lift two to four days per week, keep protein high enough to support training, avoid crash-dieting, and judge progress by strength, measurements, and how clothes fit instead of scale weight alone.

If you are losing weight

What this means if you're losing weight.

In a calorie deficit, lifting and protein decide whether the weight you lose is fat or muscle. The scale cannot show the difference, so track your lifts and your waist as well.

Ways to use it

Safe ways to apply it.

Lift while dieting, even if the scale is slower

Fat loss should not cost all your strength

Diet plus lifting beats scale-only dieting

Related questions

Questions this research helps answer.

Related guides and studies

FAQ

Quick questions

What did the study on the effect of resistance exercise on body composition, muscle strength and cardiometabolic health during dietary weight loss find?

Binmahfoz et al. (2025, BMJ Open Sport & Exercise Medicine, PMID 40909191) found that combining resistance exercise with dietary weight loss improved fat-mass loss, protected fat-free mass, and improved muscle strength compared with diet alone in adults living with overweight or obesity. The study did not show a meaningful extra drop in total bodyweight, which is why the practical win is better body composition rather than a faster scale drop.

Does resistance exercise improve cardiometabolic health during dietary weight loss?

The review included cardiometabolic outcomes, but the clearer and more reliable signal was for body composition and strength: more fat-mass loss, better fat-free-mass protection, and stronger muscle performance. Treat cardiometabolic changes as a possible benefit that still depends on the whole plan, not as the main promise of lifting during weight loss.

Should you lift weights while dieting if the scale does not move faster?

Yes. Scale weight only tells you total mass. During dietary weight loss, resistance exercise gives your body a reason to keep muscle and strength while the calorie deficit pulls from stored fat. That is why a smart diet phase tracks strength, waist measurements, photos, energy, and consistency alongside bodyweight.

What is the practical takeaway from this study?

During a diet phase, lifting may not make the scale drop faster, but it can improve fat-mass loss, protect fat-free mass, and preserve strength. Keep the plan simple: lift two to four days per week, keep protein high enough to support training, avoid crash-dieting, and judge progress by strength, measurements, and how clothes fit instead of scale weight alone.

What does this study not prove?

The strongest findings were body composition and strength outcomes. The review did not show that resistance exercise makes the scale drop faster, fixes every cardiometabolic marker, or guarantees the same response for every person living with overweight or obesity.

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